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Learning objectives

Decompensated cirrhosis is characterized by a sudden deterioration of chronic liver disease that may result in multi-organ failure. This increasingly recognized entity can develop at any time during the course of liver disease and it is associated with high short term mortality. Our understanding of the determinants of decompensated cirrhosis and the availability of effective therapeutic options remain limited. It is therefore imperative that the level of knowledge and recognition of this syndrome be increased. A multi-pronged approach is required to adequately address this syndrome from the perspectives of prevention, diagnosis, management, treatment and research.

Upon completion of the conference, participants will be able to:

  • Recognize the current status of epidemiology, pathophysiology, diagnosis, clinical presentation, and therapy of decompensated cirrhosis.
  • Identify gaps in our current understanding of decompensated cirrhosis that need to be filled by future research.

Furthermore, the knowledge gained from this meeting can be applied and enhanced as the interactive format of the meeting will strive to:

  • Foster informal exchange between leaders in the field and engage young investigators.
  • Foster research collaboration on decompensated cirrhosis within Canada, North America and beyond.

Co-chairs

Christopher Rose
Dean Karvellas

Organizing committee

Julien Bissonnette
Rick Schreiber

International speakers

Rajiv Jalan
Jasmohan Bajaj
Todd Stravitz
Manuela Merli
Julia Wendon
Scott Nyberg
Patrick Kamath
Jody Olson
Michael Lucey

National speakers

  • Christopher Rose
  • Mark Swain
  • Juan Abraldes
  • Julien Bissonnette
  • Vladimir Marquez
  • Aldo Montano-Loza
  • Phil Wong
  • Puneeta Tandon
  • François Carrier
  • Dean Karvellas
  • Florence Wong
  • Jordan Feld

Program

Print Program Booklet


Friday October 12th

17:00

Welcome reception

19:00

Dinner

19:30
Acute-on-chronic liver failure
by Rajiv Jalan (University College London, UK)

Saturday October 13th

  • Chairs : Rajiv Jalan and Puneeta Tandon

    Learning Objectives

    At the end of this session, participants will/will be able to:

    • Understand the pathophysiology of hepatic encephalopathy
    • Identify the impact of HE on cognitive function
    • Review diagnosis and management of HE
    8:00
    Gut-liver-brain axis
    by Christopher Rose (CRCHUM, Montréal, Québec)
    8:30
    Cognitive decline pre-cirrhosis
    by Mark Swain (University of Calgary, Calgary, Alberta)
    9:00
    Diagnosis and management of hepatic encephalopathy
    by Jasmohan Bajaj (Virginia Commonwealth University, USA)

    9:30

    Coffee break


  • Chairs : Jody Olson and Julia Wendon

    Learning Objectives

    At the end of this session, participants will/will be able to:

    • Discuss endoscopic and non-invasive variceal screening methods in decompensated cirrhosis
    • Review the management of variceal bleeding
    • Understand abnormalities in coagulation/hemostasis in decompensated cirrhosis
    • Evaluate the role of anticoagulation in cirrhotic patients with thromboembolic complications
    10:00
    Primary variceal screening: Is endoscopy required?
    by Juan Abraldes (University of Alberta, Edmonton, Alberta)
    10:30
    Management of variceal bleeding
    by Julien Bissonnette (CHUM, Montréal, Québec)
    11:00
    When to treat portal vein thrombosis
    by Vladimir Marquez (Vancouver General Hospital, Vancouver, British-Columbia)
    11:30
    Coagulopathy
    by Todd Stravitz (Virginia Commonwealth University, USA)

    12:00

    Lunch


  • Learning Objectives

    At the end of this session, participants will/will be able to:

    • Understand the impact of sarcopenia in cirrhosis
    • Review current concepts about nutrition in cirrhosis/ACLF
    • Describe the role of palliative care in ACLF/cirrhotic patients declined for liver transplant
    • Recognize the impact of HE on driving
    Chairs : Jasmohan Bajaj and Scott Nyberg
    13:30
    Impact of sarcopenia
    by Aldo Montano-Loza (University of Alberta, Edmonton, Alberta)
    14:00
    Nutrition and cirrhosis
    by Manuela Merli (Sapienza University of Rome, Italy)
    14:30

    Breakout session A

    1. Hepatic encephalopathy and driving
    by Phil Wong (McGill University, Montréal, Québec)
    2. Palliative care in the cirrhotic patient
    by Puneeta Tandon and Amanda Brisebois (University of Alberta, Edmonton, Alberta)

    15:30

    Coffee break


  • Chairs : Patrick Kamath and Michael Lucey

    Learning Objectives

    At the end of this session, participants will/will be able to:

    • Discuss critical care management of the ACLF patient with multiorgan failure
    • Review the evidence for artificial/bioartificial liver support in ACLF
    • Review perioperative challenges in the ACLF patient undergoing liver transplant
    • Understand the challenges of determining futility in ACLF patient undergoing liver transplantation
    16:00
    Critical care management of the ACLF patient in the ICU
    by Julia Wendon (King's College Hospital, UK)
    16:30
    Artificial liver support
    by Scott Nyberg (Mayo Clinic, USA)
    17:00
    Perioperative management during liver transplantation
    by François Carrier (CHUM, Montréal, Québec)
    17:30
    Liver transplant: Challenges in predicting futility
    by Dean Karvellas (University of Alberta, Edmonton, Alberta)

19:00

Reception

19:30

Dinner

20:00
Towards a unified definition and future research opportunities
by Patrick Kamath (Mayo Clinic, USA)

Sunday October 14th

  • Chairs : Marc Bilodeau and Mark Swain

    Learning Objectives

    At the end of this session, participants will/will be able to:

    • Review the epidemiology and therapies of acute kidney injury (AKI) in cirrhosis
    • Recognize the impact of sepsis in cirrhosis and the rational use of antibiotics
    • Understand the role and challenges of Hepatitis C Virus (HCV) eradication in decompensated cirrhosis
    • Discuss evolving role of liver transplant in patients with alcohol-related liver disease
    08:00

    Breakout session B

    1. Sepsis and antimicrobials: A clinical challenge
    by Jody Olson (University of Kansas Medical Center)
    2. Controversies in liver transplantation: Alcoholic hepatitis
    by Michael Lucey (University of Wisconsin, USA)
    09:00
    Hepatorenal syndrome/AKI in cirrhosis
    by Florence Wong (University Health Network, Ontario, Canada)
    09:30
    Benefit of hepatitis C treatment in decompensated cirrhosis
    by Jordan Feld (University Health Network, Ontario, Canada)

    10:00

    Coffee break


  • 10:30
    Case reports with treatment/management strategies – “live" survey

12:00

End of the meeting

13:30

Mini-putt tournament

Venue

To book a room please contact Brookstreet Hotel directly via email at reservations@brookstreet.com or by telephone at 1-888-826-2220
To get the discounted rate, quote the following code: CASL-STC

hotel

Brookstreet Hotel

525 Legget Dr,
Kanata ON, K2K 2W2

Brookstreet Hotel

525 Legget Dr,
Kanata ON, K2K 2W2

hotel

Registration

All meals are included with registration (2 dinners, 2 breakfasts and 1 lunch)

Click here for CASL membership

 
 
CASL Members
Non-CASL Members
Trainees
Early Registration
Before 31/07/2018
200$
400$
100$
Registration
After 01/08/2018
250$
450$
150$
Late registration
After 03/10/2018
300$
500$
200$

Contact us

If you have questions or comments, write us at info@casl-stc-2018.ca

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